发明名称 |
METHODE DE CRIBLAGE DE COMPOSES ANTIRETROVIRAUX ET VACCIN |
摘要 |
The present invention relates to an in vitro method of screening for candidate compounds capable of being used for the preventative and/or curative treatment of a disease caused by a retrovirus in which the candidate compound which modulates the expression and/or the activity of the SAMHD1 protein is identified as a candidate compound capable of being used for the preventative and/or curative treatment of a disease caused by a retrovirus. The invention also relates to a vaccine composition and an immunogenic composition, comprising i) an inhibitor of the expression and/or of the activity of the SAMHD1 protein and ii) at least one antigen of a retrovirus. |
申请公布号 |
FR2973040(B1) |
申请公布日期 |
2016.04.15 |
申请号 |
FR20110052394 |
申请日期 |
2011.03.23 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) |
发明人 |
BENKIRANE MONSEF;LAGUETTE NADINE;SOBHIAN BIJAN |
分类号 |
C12Q1/00;A61K31/7105;A61K35/12;A61K39/395;A61P37/04;C12Q1/68;G01N33/68 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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