发明名称 N-PYRIDINYL ACETAMIDE DERIVATIVES AS WNT SIGNALLING PATHWAY INHIBITORS
摘要 This invention relates to compounds. More specifically, the invention relates to compounds useful as inhibitors of the Wnt signalling pathway. Specifically, inhibitors of Porcupine (Porcn) are contemplated by the invention. In addition the invention contemplates processes to prepare the compounds and uses of the compounds. The compounds of the invention may therefore be used in treating conditions mediated by the Wnt signalling pathway, for example treating cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia; or enhancing the effectiveness of an anti-cancer treatment.
申请公布号 WO2016055790(A1) 申请公布日期 2016.04.14
申请号 WO2015GB52943 申请日期 2015.10.08
申请人 REDX PHARMA PLC 发明人 BHAMRA, INDER;MATHIESON, MICHAEL;DONOGHUE, CRAIG;TESTAR, RICHARD
分类号 C07D471/04;A61K31/437;A61K31/519;A61P35/00;C07D487/04 主分类号 C07D471/04
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