发明名称 COSOLVENT FORMULATION
摘要 PROBLEM TO BE SOLVED: To provide a vehicle composition having a synergistic preservative effect that requires no antioxidant, contains no additives that would lead to an increase in the levels of aluminum, has a sufficient preservative effect in solution agents, such as injections, and may be terminally sterilized.SOLUTION: The invention relates to a sterilized, self-preserved, synergistic antimicrobial vehicle composition consisting essentially of water, a low molecular weight alcohol in the range of about 25% to about 30% (v/v), and a glycol derivative in the range of about 20% to about 25% (v/v). Preferably, the small molecule alcohol is ethanol and the glycol derivative is glycerin or propylene glycol.SELECTED DRAWING: Figure 1
申请公布号 JP2016053046(A) 申请公布日期 2016.04.14
申请号 JP20150204318 申请日期 2015.10.16
申请人 ABBVIE INC 发明人 LUKCHIU LI;EDWARD A PEC;ROBINSON DANIEL H;STEPHENS DENNIS A;KATHEE JANTZI;MAY THOMAS B;JOHN P OBERDIER
分类号 A61K47/10;A61K9/00;A61K9/08;A61K31/59;A61K47/00;A61P3/02;A61P43/00 主分类号 A61K47/10
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