METHODS OF TREATMENT OF A NEUROLOGICAL DISORDER USING ELECTRICAL NERVE CONDUCTION BLOCK

摘要

Described herein are methods of treating various neurological disorders using electrical nerve conduction block (ENCB) without causing electrochemical damage. Examples of the various neurological disorders can include pain, muscle spasticity, hyperhidrosis, vertigo, sialorrhea, or the like. The methods can include placing an electrode contact in electrical communication with a nerve that transmits a signal related to the neurological disorder. The method also includes applying an ENCB to the nerve through the electrode contact. The electrode contact can include a high charge capacity material that prevents formation of damaging electrochemical reaction products at a charge delivered by the ENCB. The method also includes blocking transmission of the signal related to the neurological disorder through the nerve with the ENCB to treat the neurological disorder.

主权项

1. A method for reducing pain in a subject, the method comprising:
placing an electrode contact in electrical communication with a nerve that transmits a signal related to the pain; applying an electrical nerve conduction block (ENCB) to the nerve through the electrode contact, wherein the electrode contact comprises a high charge capacity material that prevents formation of damaging electrochemical reaction products at a charge delivered by the ENCB; and blocking transmission of the signal related to the pain through the nerve with the ENCB to reduce the pain.