发明名称 THERAPEUTIC AGENT AND INSPECTION METHOD FOR DISEASES CAUSED BY NEUTROPHIL ACTIVATION
摘要 PROBLEM TO BE SOLVED: To provide a therapeutic agent for diseases caused by neutrophil activation, the therapeutic agent containing a neutrophil activation regulatory agent which has a neutrophil activation controlling function and a neutrophil activation regulating function; and also to provide an inspection method for diseases caused by neutrophil activation.SOLUTION: The invention provides a therapeutic agent for inflammatory diseases associated with neutrophil activation the therapeutic agent using a neutrophil activation regulatory agent containing a histidine rich glycoprotein (HRG) as an active ingredient, and a neutrophil-endothelial cell interaction inhibitor containing the HRG as an active ingredient; and an inspection method for inflammatory diseases associated with neutrophil activation by measuring the amount of HRG in blood.SELECTED DRAWING: Figure 13
申请公布号 JP2016053022(A) 申请公布日期 2016.04.14
申请号 JP20150172691 申请日期 2015.09.02
申请人 OKAYAMA UNIV 发明人 NISHIBORI MASAHIRO;MORI HIDEJI;WAKE HIDENORI;TAKAHASHI HIDEO;LIU KEYUE;TESHIGAHARA TADASHI;SAKAGUCHI MASAKIYO
分类号 A61K38/00;A61P1/04;A61P1/16;A61P1/18;A61P3/02;A61P3/10;A61P7/08;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P21/00;A61P25/00;A61P25/04;A61P25/08;A61P29/00;A61P31/04;A61P35/00;A61P37/06;A61P43/00;C12Q1/68;G01N33/53 主分类号 A61K38/00
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