发明名称 |
THERAPEUTIC AGENT AND INSPECTION METHOD FOR DISEASES CAUSED BY NEUTROPHIL ACTIVATION |
摘要 |
PROBLEM TO BE SOLVED: To provide a therapeutic agent for diseases caused by neutrophil activation, the therapeutic agent containing a neutrophil activation regulatory agent which has a neutrophil activation controlling function and a neutrophil activation regulating function; and also to provide an inspection method for diseases caused by neutrophil activation.SOLUTION: The invention provides a therapeutic agent for inflammatory diseases associated with neutrophil activation the therapeutic agent using a neutrophil activation regulatory agent containing a histidine rich glycoprotein (HRG) as an active ingredient, and a neutrophil-endothelial cell interaction inhibitor containing the HRG as an active ingredient; and an inspection method for inflammatory diseases associated with neutrophil activation by measuring the amount of HRG in blood.SELECTED DRAWING: Figure 13 |
申请公布号 |
JP2016053022(A) |
申请公布日期 |
2016.04.14 |
申请号 |
JP20150172691 |
申请日期 |
2015.09.02 |
申请人 |
OKAYAMA UNIV |
发明人 |
NISHIBORI MASAHIRO;MORI HIDEJI;WAKE HIDENORI;TAKAHASHI HIDEO;LIU KEYUE;TESHIGAHARA TADASHI;SAKAGUCHI MASAKIYO |
分类号 |
A61K38/00;A61P1/04;A61P1/16;A61P1/18;A61P3/02;A61P3/10;A61P7/08;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P21/00;A61P25/00;A61P25/04;A61P25/08;A61P29/00;A61P31/04;A61P35/00;A61P37/06;A61P43/00;C12Q1/68;G01N33/53 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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