| 发明名称 |
Site-Specific Immobilization of DNA Origami Structures on Solid Substrates |
| 摘要 |
The present invention relates to methods for the site-specific immobilization of DNA origami structures on solid substrates, as well as to respective assemblies comprising DNA origami structures immobilized on a solid substrate and uses thereof. |
| 申请公布号 |
US2016102344(A1) |
申请公布日期 |
2016.04.14 |
| 申请号 |
US201514881412 |
申请日期 |
2015.10.13 |
| 申请人 |
Karlsruher Institut Für Technologie |
发明人 |
Niemeyer Christof;Meyer Rebecca;Angelin Alessandro;Foulkes Nicholas S.;Kassel Olivier;Weigel Simone;Bauer Jens;Scharnweber Tim |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the site-specific immobilization of DNA origami structures on a solid substrate, said method comprising the steps of:
(a) providing at least one type of DNA origami structure having at least one type of first structural feature; (b) providing a pre-patterned solid substrate that is functionalized with at least one type of a second structural feature, wherein the second structural feature is capable of binding to the first structural feature on the DNA origami structure; and (c) incubating the solid substrate of step (b) with the at least one type of DNA origami structure of step (a). |
| 地址 |
Karlsruhe DE |
