发明名称 |
ANTIBIOTIC ACTIVITY OF IRON SEQUESTRING POLYMERS |
摘要 |
A polymeric metal sequestrant providing antibiotic activity is provided. The polymeric metal sequestrant comprises a polyamine polymer covalently coupled to a chelator, wherein the chelator has a benzene ring with more than one hydroxyl group at any position that is free. The polymeric metal sequestrant is effective in inhibiting and preventing bacterial infections and displays synergistic effects in combination with traditional antibiotics. |
申请公布号 |
WO2016057754(A1) |
申请公布日期 |
2016.04.14 |
申请号 |
WO2015US54627 |
申请日期 |
2015.10.08 |
申请人 |
THE UNIVERSITY OF KANSAS |
发明人 |
BERKLAND, CORY;RIVERA, MARIO;ESHELMAN, KATE;QIAN, JIAN;EL-GENDY, NASHWA |
分类号 |
A61K31/785;A61K47/48;C08G59/50 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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