METHOD OF DIAGNOSING AND TREATING ALZHEIMER'S DISEASE

摘要

Alzheimer's disease is treated by attacking hyperactive microglia preferably before excessive beta amyloid is built up by administering tin-117m-DOTA annexin V. This compound in low radioactive doses selectively binds to the aged hyperactive microglia and emits a conversion electron which effectively induces apoptosis in the hyperactive microglia. A follow-up treatment of tin-annexin A1 can be administered to repair the blood brain barrier. The annexin A1 assists in the repair of the blood-brain barrier and the associated tin-117m will induce apoptosis in aged hyperactive microglia associated with the blood brain barrier.

主权项

1. A method of treating Alzheimer's disease comprising administering to an individual having Alzheimer's disease an amount of tin-117m annexin effective to induce apoptosis in aged hyperactive microglia cells in the brain.