发明名称 A PROCESS FOR PREPARING GLYCOPYRRONIUM BROMIDE
摘要 The invention relates to a process for preparing glycopyrronium bromide in the form of [R,S] and [S.R] diastereoisomers, the method consisting in separation of these desired diastereoisomers from the mixture of [R,S3, [S,R], [R,R] and [S,S] diastereoisomers by means of two or more controlled crystallizations from a solution of a solvent selected from the group consisting of 1-propanol, 2-propanol, 1-butanol, and tert-butanol.
申请公布号 WO2016055033(A1) 申请公布日期 2016.04.14
申请号 WO2015CZ00110 申请日期 2015.09.30
申请人 ZENTIVA, K.S. 发明人 OBADALOVA, IVA;CHVOJKA, TOMAS;HRUBY, JAN;DAMMER, ONDREJ;TKADLECOVA, MARCELA;REITMAJER, JOSEF;NOVOTNA, NADEZDA;LEHNERT, PETR
分类号 C07D207/12;A61K31/40;A61P11/08 主分类号 C07D207/12
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