发明名称 COMBINATION OF LYSINE-SPECIFIC DEMETHYLASE 1 INHIBITOR AND THROMBOPOIETIN AGONIST
摘要 The present invention relates to a method of treating cancer and pre-cancerous syndromes in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering 4- ((4-((((1R,2S)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)methyl)benzoic acid, or a pharmaceutically acceptable salt thereof, and 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazin o]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid, or a pharmaceutically acceptable salt thereof, to a human in need thereof.
申请公布号 WO2016055935(A1) 申请公布日期 2016.04.14
申请号 WO2015IB57637 申请日期 2015.10.06
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED 发明人 ERICKSON-MILLER, CONNIE L.;KRUGER, RYAN G.;STONE, NICOLE LEE
分类号 A61K45/06;A61K31/4152;A61K31/445;A61P35/00;A61P35/02 主分类号 A61K45/06
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