发明名称 |
Factor XII inhibitors for the treatment of silent brain ischemia and ischemia of other organs |
摘要 |
Silent brain ischemia (SBI) or ischemia of other organs can result from an embolism that is introduced into the arterial system during a medical procedure. The application provides a method of administering a FXII inhibitor in a patient receiving a medical procedure and animal models useful for studying ischemia including SBI and ischemia in other organs, and for evaluating candidate therapeutics. |
申请公布号 |
AU2012224510(B2) |
申请公布日期 |
2016.04.14 |
申请号 |
AU20120224510 |
申请日期 |
2012.03.09 |
申请人 |
CSL BEHRING GMBH;THE GENERAL HOSPITAL CORPORATION |
发明人 |
NAHRENDORF, MATTHIAS;WEISSLEDER, RALPH;DICKNEITE, GERHARD;STOLL, GUIDO;NOLTE, MARC |
分类号 |
C07K16/36;A61K38/55;A61K38/57;A61K39/395;A61K49/00;A61P9/10;G01N33/50 |
主分类号 |
C07K16/36 |
代理机构 |
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地址 |
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