发明名称 |
Consumable Cryopreserved Cells Transiently Overexpressing Gene(s) Encoding Drug Transporter Protein(s) and/or Drug Metabolizing Enzyme(s) |
摘要 |
The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes. |
申请公布号 |
US2016102131(A1) |
申请公布日期 |
2016.04.14 |
申请号 |
US201514972012 |
申请日期 |
2015.12.16 |
申请人 |
Corning Incorporated |
发明人 |
Li Na;Wang Jie;Patten Christopher J. |
分类号 |
C07K14/705;A01N1/02;C12N15/85 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
1. A cryopreserved recombinant cell comprising one or more transiently overexpressed genes encoding a drug transporter protein, wherein activity of the drug transporter protein is detectable in a population of the cryopreserved recombinant cell following thaw from cryopreservation. |
地址 |
Corning NY US |