| 发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING PKK EXPRESSION |
| 摘要 |
Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate PKK-associated diseases, disorders, and conditions. |
| 申请公布号 |
WO2015168532(A3) |
申请公布日期 |
2016.04.14 |
| 申请号 |
WO2015US28765 |
申请日期 |
2015.05.01 |
| 申请人 |
IONIS PHARMACEUTICALS, INC. |
发明人 |
PRAKASH, THAZHA P.;SETH, PUNIT P.;SWAYZE, ERIC E.;FREIER, SUSAN M.;BUI, HUYNH-HOA |
| 分类号 |
A61K31/7088;A61K31/7125;C12N15/113 |
主分类号 |
A61K31/7088 |
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