EXOGENOUS TERMINATORS FOR CONTROLLING FUNGAL GENE EXPRESSION

摘要

Provided herein are exogenous terminator sequences for use in fungi cell transcriptional termination.

主权项

1. An exogenous fungi transcription terminating nucleic acid sequence comprising:
(i) an efficiency nucleic acid sequence of the formula (TA)n1, wherein n1 is an integer from 4 to 20; (ii) a positioning nucleic acid sequence of the formula AAWAAA, wherein W is A or T; and (iii) a polyadenylation site nucleic acid sequence comprising the sequence (N)n4Y-An2, wherein N is A, C, T, or G; n4 is an integer from 0 to 10; Y is a polyadenylation site nucleotide and is C or T; and n2 is an integer from 3 to 50.