发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING FOXP3 EXPRESSION |
摘要 |
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of FOXP3. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of FOXP3. Methods for modulating expression of FOXP3 using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of FOXP3. |
申请公布号 |
EP3004354(A1) |
申请公布日期 |
2016.04.13 |
申请号 |
EP20140807355 |
申请日期 |
2014.06.06 |
申请人 |
RANA THERAPEUTICS, INC. |
发明人 |
BARSOUM, JAMES;SEVERGNINI, MARIANO;MCSWIGGEN, JAMES |
分类号 |
C12N15/113;A61K48/00;A61P37/04 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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