Method for treating cardiac diseases using BET inhibitors including JQ1 are provided. Methods for treating cardiac hypertrophy, method for treating heart failure not arising from inflammation, methods for treating myocardial infarction, methods for cardioprotection and methods for inhibiting restenosis are described herein. The methods involve the use of effective amounts of BET inhibitors such as JQ1.
申请公布号
EP3003312(A1)
申请公布日期
2016.04.13
申请号
EP20140804188
申请日期
2014.05.28
申请人
DANA-FARBER CANCER INSTITUTE, INC.;CASE WESTERN RESERVE UNIVERSITY;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
发明人
HALDAR, SAPTARSI, M.;BRADNER, JAMES, E.;BROWN, JONATHAN, D.
