发明名称 |
TOPICAL AQUEOUS OPHTHALMIC COMPOSITIONS CONTAINING A 1H-INDOLE-1-CARBOXAMIDE DERIVATIVE AND USE THEREOF FOR TREATMENT OF OPHTHALMIC DISEASE |
摘要 |
The present invention is directed to the provision of a multi-dose topical ophthalmic composition containing a 1H-indole-1-carboxamide and use thereof for treatment of ophthalmic disease. More specifically the present invention is directed to a multi-dose aqueous ophthalmic composition (e.g., a solution, a suspension, an emulsion or the like) containing a 1H-indole-1-carboxamide (e.g., N-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6-((methylamino) methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide) and use thereof for treatment of an ophthalmic disease at the back of the eye such as age related macular degeneration (AMD). |
申请公布号 |
EP3003270(A1) |
申请公布日期 |
2016.04.13 |
申请号 |
EP20140736523 |
申请日期 |
2014.06.04 |
申请人 |
NOVARTIS AG |
发明人 |
GHOSH, MALAY;ADAMS, CHRISTOPHER MICHAEL;DODD, STEPHANIE KAY;POOR, STEPHEN HEDRICK |
分类号 |
A61K9/00;A61K9/08;A61K31/506;A61K31/519;A61K47/02;A61K47/10;A61K47/18;A61K47/26;A61K47/32;A61K47/34;A61K47/38;A61P27/02 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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