发明名称 |
LIPOSOMES FOR MODULATING WISKOTT-ALDRICH SYNDROME PROTEIN |
摘要 |
Embodiments of the invention relate to liposomes comprising: a lipid bilayer having an internal cavity; a therapeutic agent within the internal cavity configured to modify expression or degradation of WASp in a cell; and a targeting moiety external to the lipid bilayer configured to target an extracellular domain of a cell. Embodiments of the invention relate to methods of treatment of disease comprising administering the liposomes. Novel pharmaceutical compositions are also disclosed. |
申请公布号 |
EP3003275(A1) |
申请公布日期 |
2016.04.13 |
申请号 |
EP20140808354 |
申请日期 |
2014.06.03 |
申请人 |
BAR-ILAN UNIVERSITY |
发明人 |
BARDA-SAAD, MIRA |
分类号 |
A61K9/127;A61K38/00;A61P7/00;C12N15/113;C12N15/88 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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