| 发明名称 |
BICYCLO[6.1.0]NON-4-YNE REAGENTS FOR CHEMICAL MODIFICATION OF OLIGONUCLEOTIDES |
| 摘要 |
The present invention provides for compounds of Formulae I and II: wherein 1R, 2R, L, X, q, Z, A, and B have any of the values disclosed in the specification. Compounds of Formulae I and II are useful as reagents to introduce bicyclo[6.1.0]non-4-yne groups into oligonucleotide chains to serve as points of attachment for chemical tags. |
| 申请公布号 |
EP2753607(B1) |
申请公布日期 |
2016.04.13 |
| 申请号 |
EP20120768941 |
申请日期 |
2012.09.07 |
| 申请人 |
BERRY AND ASSOCIATES, INC.;SYNAFFIX B.V. |
发明人 |
HODGES, JOHN, COOKE;VAN DELFT, FLORIS, LOUIS;VAN BERKEL, SANDER, SEBASTIAAN;VERKADE, JORGE;BERRY, DAVID, A. |
| 分类号 |
C07D239/22;C07F9/02;G01N33/531;G01N33/68 |
主分类号 |
C07D239/22 |
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