发明名称 17alpha-monoesters and 17alpha,21-diesters of cortexolone for use in the treatment of tumors
摘要 The present invention provides certain cortexolone derivatives of formula (I) and the same for use as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. Another aspect of the invention relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of said pharmaceutical compositions as antitumor medicinal products.
申请公布号 EP3006453(A1) 申请公布日期 2016.04.13
申请号 EP20140188063 申请日期 2014.10.08
申请人 COSMO TECHNOLOGIES LTD. 发明人 GERLONI, MARA
分类号 C07J5/00;A61K31/573;A61P35/00 主分类号 C07J5/00
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