发明名称 NOVEL SUICIDAL LSD1 INHIBITORS TARGETING SOX2-EXPRESSING CANCER CELLS
摘要 Disclosed are inhibitors of lysine-specific demethylase I (LSD1); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating cancers characterized by the presence of Sox2 using the compounds and compositions Also disclosed are methods of treating cancers characterized by the presence of Sox2 using inhibitors of LSD1 and/or histone deacetylation I (HDAC1). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
申请公布号 EP3003301(A2) 申请公布日期 2016.04.13
申请号 EP20140804229 申请日期 2014.05.30
申请人 THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA 发明人 ZHANG, HUI
分类号 A61K31/27;A61K45/06;A61P35/00;C07C217/74;C07C271/24;C07D207/14;C07D295/13 主分类号 A61K31/27
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