| 发明名称 |
DNA MODIFYING FUSION PROTEINS AND METHODS OF USE THEREOF |
| 摘要 |
Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array or zinc finger, and a catalytic domain comprising a sequence that catalyzes hydroxylation of methylated cytosines in DNA, and methods of use thereof. |
| 申请公布号 |
EP2879693(A4) |
申请公布日期 |
2016.04.13 |
| 申请号 |
EP20130797024 |
申请日期 |
2013.05.29 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
JOUNG, J. KEITH;MAEDER, MORGAN;ANGSTMAN, JAMES |
| 分类号 |
A61K38/17;A61K48/00;A61P9/00;A61P25/18;A61P35/00;C07K14/435;C07K19/00;C12N15/62 |
主分类号 |
A61K38/17 |
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代理人 |
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