| 摘要 |
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I)
(wherein:
R 1 and R 2 are, the same or different, each (Z)-pentadecenyl, (Z)-hexadecenyl or ( Z )-heptadecenyl, etc,
a and b are, the same or different, each 0 to 3,
m is 1,
the dotted line is a single bond or absent,
X 1 and X 2 are hydrogen atoms, or are combined together to form a single bond or alkylene,
X 4 is absent or is alkylene, etc
X 3 is absent or is alkyl, etc,
Y is absent or anion,
L 3 is a single bond, -CO-O- or -O-CO-
R 3 is hydrogen atoms, alkyl, etc,
L 1 and L 2 are -0-, -CO-O- or -O-CO-) and the like. |
