发明名称 ベンゾヘテロサイクル誘導体の癌の予防及び治療又は癌転移抑制のための用途
摘要 This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising benzo-heterocycle derivative or pharmaceutically acceptable salts thereof as an active ingredient. The present inventors confirmed that KRS has an effect on cancer metastasis by facilitating cancer (or tumor) cell migration through interaction with 67LR, and also found that a substance inhibiting the interaction between KRS and 67LR can prevent and treat cancer by inhibiting cancer cell metastasis. Accordingly, the composition of the present invention can inhibit cancer metastasis, and thus provide a novel means for prevention and treatment of cancer.
申请公布号 JP5901529(B2) 申请公布日期 2016.04.13
申请号 JP20120537820 申请日期 2010.11.05
申请人 メディシナル バイオコンバージェンス リサーチ センター 发明人 キム, サンフン;チョイ, ジンウー;イ, ジンヨン;キム, テギュ;ハン, キョンヒ;ヤン, チソン;イ, チュルホ
分类号 A61K31/423;A61K31/4045;A61K31/428;A61P35/04 主分类号 A61K31/423
代理机构 代理人
主权项
地址