Methods, devices, and kits for microjet drug delivery

摘要

Described here are methods, devices, and kits for microjet drug delivery. The devices described here may be modular or non-modular. The modular devices typically include a first module having a drug reservoir and a nozzle in fluid communication with the drug reservoir and a second module having an actuator and a power supply. The power supply provides power to the actuator and when the first and second modules are coupled, the actuator is capable of acting on a dispensing member causing it to dispense a drug in liquid form from the drug reservoir via the nozzle at a velocity sufficient to penetrate skin. Other devices described include a nozzle, a reservoir in fluid communication with the nozzle, a dispensing member, and an actuator. In these devices, the nozzle has at least one feature that enhances nozzle contact with the skin in order to reduce lateral drug leakage about the nozzle.

主权项

1. A modular drug delivery device comprising:
a first module comprising a drug reservoir and a nozzle having a first end and a second end, where the first end is in fluid communication with the drug reservoir, the first module having a basal surface that contacts skin during use, and where the second end of the nozzle terminates at the basal surface to define a skin-nozzle interface; and a second module comprising an actuator and a power supply, wherein the power supply provides power to the actuator and wherein the first and second modules are capable of being releasably coupled to form a modular drug delivery device, and wherein when the first and second modules are coupled, the actuator is capable of acting on a dispensing member causing it to dispense a drug in liquid form from the nozzle at a velocity sufficient to penetrate skin.