发明名称 Lactic acid bacteria and compositions containing them against bacterial colds
摘要 The invention describes a microorganism of the order of lactic acid bacteria or an analog, fragment, derivative, mutant or combination thereof, wherein the microorganism, or analog, fragment, derivative, mutant or combination thereof can coaggregate with Streptococcus pyogenes.
申请公布号 US9308227(B2) 申请公布日期 2016.04.12
申请号 US201214118091 申请日期 2012.05.16
申请人 ORGANOBALANCE MEDICAL AG 发明人 Lang Christine;Raab Andreas;Bolotina Natalia
分类号 A61K35/744;C12Q1/04;C12R1/225;A61K35/74;A23L1/30;C12N1/20;A23K1/00;A61K35/747;A61K45/06 主分类号 A61K35/744
代理机构 Agris & von Natzmer LLP 代理人 von Natzmer Joyce;Agris & von Natzmer LLP
主权项 1. A method for identifying and/or selecting a lactic acid bacterium that coaggregates with Streptococcus pyogenes, wherein the method comprises: incubating Streptococcus pyogenes under conditions under which Streptococcus pyogenes forms a biofilm, adding the lactic acid bacterium to be investigated to a mixture for coaggregation between the Streptococcus pyogenes and the lactic acid bacterium and incubation of the mixture, and separating any unbound lactic acid bacteria by removing a supernatant and determining a presence of coaggregated lactic acid bacteria in the biofilm formed by Streptococcus pyogenes.
地址 Berlin DE