Compound useful for the treatment of degenerative and inflammatory diseases

摘要

A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I:;
or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6.

主权项

1. A method for the treatment of psoriasis, comprising administering an amount of a compound according to Formula I:or a pharmaceutically acceptable salt thereof sufficient to effect said treatment.