主权项 |
1. A thiazolopyridinone of formula (I) and/or a salt thereof in which R1 represents hydrogen, halogen, nitro, cyano, (C1-C6)-alkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, (C1-C6)-alkoxy, (C1-C6)-alkylthio, (C1-C6)-alkylsulfinyl, (C1-C6)-alkylsulfonyl, (C3-C6)-cycloalkyl, (C1-C6)-alkoxy-(C1-C6)-alkyl, di-(C1-C6)-alkoxy-(C1-C6)-alkyl or (C1-C6)-alkylthio-(C1-C6)-alkyl, each of which is substituted by n halogen atoms, R2 represents hydrogen, (C1-C6)-alkyl, (C2-C6)-alkenyl, (C3-C6)-alkynyl, (C3-C6)-cycloalkyl, (C1-C6)-alkoxy-(C1-C6)-alkyl or di-(C1-C6)-alkoxy-(C1-C6)-alkyl, (C1-C6)-alkylthio-(C1-C6)-alkyl, (C1-C6)-alkylsulfinyl-(C1-C6)-alkyl, (C1-C6)-alkylsulfonyl-(C1-C6)-alkyl, (C3-C6)-cycloalkyl-(C1-C6)-alkyl, cyano-(C1-C6)-alkyl, each of which is substituted by n halogen atoms, or phenyl or benzyl, each of which is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, R3 represents hydroxy, O—C(═O)R7, O—C(=L)MR8, O—SO2R9, O—P(=L)R10R11, O—C(=L)NR12R13, O-E or O—R14, R4 represents R4a or R4b, R4a represents aryl which is substituted by n radicals R5 and one radical R6, R4b represents 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 1-pyrrolyl, 2-pyrrolyl, 3-pyrrolyl, 3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 1-pyrazolyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 1-imidazolyl, 2-imidazolyl, 4-imidazolyl, 5-imidazolyl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-oxadiazol-2-yl, 1,3,4-thiadiazol-2-yl, 1,2,4-triazol-1-yl, 1,2,4-triazol-3-yl, 1,2,4-triazol-4-yl, 1,2,4-triazol-5-yl, 1,2,3-triazol-1-yl, 1,2,3-triazol-2-yl, 1,2,3-triazol-4-yl, tetrazol-1-yl, tetrazol-2-yl, tetrazol-5-yl, indol-1-yl, indol-2-yl, indol-3-yl, isoindol-1-yl, isoindol-2-yl, benzofur-2-yl, benzothiophen-2-yl, benzofur-3-yl, benzothiophen-3-yl, benzoxazol-2-yl, benzothiazol-2-yl, benzimidazol-2-yl, indazol-1-yl, indazol-2-yl, indazol-3-yl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, 2-pyrazinyl, 1,3,5-triazin-2-yl, 1,2,4-triazin-3-yl, 1,2,4-triazin-5-yl or 1,2,4-triazin-6-yl, substituted by n radicals R5 and by m radicals R6, R5 represents hydrogen, halogen, nitro, cyano, (C1-C6)-alkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, (C1-C6)-alkoxy, (C1-C6)-alkylthio, (C1-C6)-alkylsulfinyl, (C1-C6)-alkylsulfonyl, (C3-C6)-cycloalkyl, (C1-C6)-alkoxy-(C1-C6)-alkyl or (C1-C6)-alkylthio-(C1-C6)-alkyl, each of which is substituted by n halogen atoms, R6 represents aryl or heteroaryl, each of which is substituted by s radicals R5, E represents a metal ion equivalent or an ammonium ion, L represents oxygen or sulfur, M represents oxygen or sulfur, R7 represents (C1-C6)-alkyl, (C2-C6)-alkenyl, (C1-C6)-alkoxy-(C1-C6)-alkyl, di-(C1-C6)-alkoxy-(C1-C6)-alkyl or (C1-C6)-alkylthio-(C1-C6)-alkyl, each of which is substituted by n halogen atoms, a fully saturated 3- to 6-membered ring consisting of 3 to 5 carbon atoms and 1 to 3 heteroatoms from the group consisting of oxygen, sulfur and nitrogen, which ring is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, or (C3-C6)-cycloalkyl, phenyl, phenyl-(C1-C6)-alkyl, phenoxy-(C1-C6)-alkyl or heteroaryloxy-(C1-C6)-alkyl, each of which is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, R8 represents (C1-C6)-alkyl, (C2-C6)-alkenyl, (C1-C6)-alkoxy-(C1-C6)-alkyl or di-(C1-C6)-alkoxy-(C1-C6)-alkyl, each of which is substituted by n halogen atoms, or (C3-C6)-cycloalkyl, phenyl or benzyl, each of which is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, R9, R10, R11 independently of one another represent (C1-C6)-alkyl, (C1-C6)-alkoxy, N—(C1-C6)-alkylamino, N,N-di-(C1-C6)-alkylamino, (C1-C6)-alkylthio, (C2-C6)-alkenyl or (C3-C6)-cycloalkylthio, each of which is substituted by n halogen atoms, or phenyl, benzyl, phenoxy or phenylthio, each of which is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, R12, R13 independently of one another each represent hydrogen, (C1-C6)-alkyl, (C3-C6)-cycloalkyl, (C2-C6)-alkenyl, (C1-C6)-alkoxy or (C1-C6)-alkoxy-(C1-C6)-alkyl, substituted by n halogen atoms, phenyl or benzyl, each of which is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, or R12 and R13 together with the nitrogen atom to which they are attached form a 3- to 6-membered ring containing 2 to 5 carbon atoms and in each case 0 or 1 oxygen or sulfur atoms, R14 represents (C1-C6)-alkyl, (C2-C6)-alkenyl, (C2-C6)-alkynyl, (C1-C6)-alkoxy-(C1-C6)-alkyl, (C1-C6)-alkylthio-(C1-C6)-alkyl or di-(C1-C6)-alkoxy-(C1-C6)-alkyl, each of which is substituted by n halogen atoms, (C3-C6)-cycloalkyl substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, a fully saturated 3- to 6-membered ring consisting of 3 to 5 carbon atoms and 1 to 3 heteroatoms from the group consisting of oxygen, sulfur and nitrogen, which ring is substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, phenyl, phenyl-(C1-C6)-alkyl, heteroaryl, phenoxy-(C1-C6)-alkyl or heteroaryloxy-(C1-C6)-alkyl, substituted by n radicals from the group consisting of halogen, (C1-C6)-alkyl and (C1-C6)-alkoxy, m represents 0 or 1, n represents 0, 1, 2 or 3, s represents 0, 1, 2, 3 or 4. |