ALPHA-AMINOAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

摘要

The present invention relates to an alpha-aminoamide derivative compound and a pharmaceutical composition comprising the same. According to various embodiments of the present invention, the pharmaceutical composition can overcome shortcomings of a conventional drug used as a MAO-B inhibitor. More particularly, the pharmaceutical composition reversibly suppresses MAO-B through a non-covalent bond, and thus can alleviate or remove side effects of a conventional drug which exhibits treatment efficacy by irreversibly acting with MAO-B through a covalent bond. Particularly, the novel compound of the present invention has remarkable stability and efficacy in comparison to a conventional reversible MAO-B inhibitor. The alpha-aminoamide derivative compound is represented by chemical formula 1.