发明名称 Compositions relating to anti-IL-21 receptor antibodies
摘要 The present invention provides compositions and methods relating to antigen binding proteins against IL-21 receptor.
申请公布号 US9309318(B2) 申请公布日期 2016.04.12
申请号 US201313830844 申请日期 2013.03.14
申请人 Amgen, Inc. 发明人 Gavin Marc A.;Lim Ai Ching
分类号 A61K39/39;C07K16/18;C07K16/28;A61K39/395;A61K45/06 主分类号 A61K39/39
代理机构 代理人 Machin Nathan A.
主权项 1. An isolated IL-21 receptor antigen binding protein, wherein said antigen binding protein comprises either: a. the heavy chain variable domain and the light chain variable domain of antibody 29G2 or 30G3; or b. the CDR1, CDR2, and CDR3 of the light chain variable domain sequence, and CDR1, CDR2, and CDR3 of the heavy chain variable domain sequence of the antibody 29G2 or 30G3 respectively; or c. the heavy chain variable domain of the 29G2 group or the 30G3 group of FIG. 12 and the light chain variable domain selected from the corresponding group of FIG. 13; or d. the light chain variable domain of the 29G2 group or the 30G3 group of FIG. 13, and the heavy chain variable domain selected from the corresponding group of FIG. 12; or e. the heavy chain CDR 1, 2, and 3 sequences of the antibodies of the 29G2 group or the 30G3 group, and light chain CDR 1, 2, and 3 sequences selected from the antibodies within the corresponding group of FIG. 13.
地址 Thousand Oaks CA US