Bioactive substance in a barbed suture

摘要

Barbed surgical sutures are prepared with a bioactive agent thereon. In embodiments, the bioactive agent may be an antimicrobial or clotting agent deposited within the angle formed by the barb and the suture body. Placement of the bioactive agent in the angle between the barb and suture body enhances the delivery of the bioactive agent to wound tissue at the point of contact.

主权项

1. A surgical suture comprising:
an elongated body comprising at least one filament having a proximal end and a distal end; the elongated body having barbs projecting from the elongated body towards at least one end of said suture thereby forming an angle between the barbs and the elongated body; and an effective amount of a bioactive agent disposed solely within the angle between the barbs and the elongated body.