Feline bitter taste receptors and methods

摘要

A family of novel feline bitter taste receptors, referred to as feline TAS2R (fTAS2R), are disclosed herein. Isolated polynucleotides encoding the novel feline bitter taste receptors and chimeric polypeptides are also disclosed, as are expression vectors and host cells for expression of the novel feline bitter taste receptors. Methods of identifying compounds that bind to the novel feline bitter taste receptors and modulate their activity are disclosed.

主权项

1. A polypeptide comprising
the amino acid sequence of SEQ ID NO:2, or an amino acid sequence having at least 95% homology to the sequence of SEQ ID NO:2; wherein the polypeptide is covalently bound to a label, a solid support, or a lipid monolayer.