| 发明名称 | Use of NRF2 inducers to treat epidermolysis bullosa simplex and related diseases | ||
| 摘要 | The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase II enzyme inducers. | ||
| 申请公布号 | US9308192(B2) | 申请公布日期 | 2016.04.12 |
| 申请号 | US201314025485 | 申请日期 | 2013.09.12 |
| 申请人 | The Johns Hopkins University | 发明人 | Coulombe Pierre A.;Kerns Michelle L. |
| 分类号 | A61K31/26;A61K31/00;A61K38/18;A61K31/192;A61K31/497 | 主分类号 | A61K31/26 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Corless, Esq. Peter F.;Clarke, J.D. Daniel W. |
| 主权项 | 1. A method for treating or preventing skin blistering in a patient in need thereof or at risk of developing skin blistering, comprising administering to the patient a composition comprising a therapeutically effective amount of an Nrf2 inducer. | ||
| 地址 | Baltimore MD US | ||