发明名称 Hyoscyamine dosage form
摘要 A pharmaceutical dosage form which comprises two or more different hyoscyamine formulations, at least one of the formulations being an immediate release hyoscyamine formulation and at least one other one being a controlled release hyoscyamine formulation. This abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
申请公布号 US9308164(B2) 申请公布日期 2016.04.12
申请号 US200410879506 申请日期 2004.06.30
申请人 Sovereign Pharmaceuticals, LLC 发明人 Srinivasan Viswanathan;Brown Ralph;Brown David;Patel Himanshu;Menendez Juan Carlos;Suphasawud Somphet Peter
分类号 A61K31/46;A61K9/00;A61K9/24 主分类号 A61K31/46
代理机构 Abel Law Group, LLP 代理人 Abel Law Group, LLP
主权项 1. A pharmaceutical dosage form which comprises at least one of hyoscyamine and a pharmaceutically acceptable salt thereof, wherein the dosage form comprises two or more hyoscyamine formulations and at least one of the formulations is an immediate release formulation and at least one other one of the formulations is a controlled release formulation and the at least one immediate release formulation is capable of providing a hyoscyamine plasma concentration within a therapeutic range for a first period and the at least one controlled release formulation is capable of providing a hyoscyamine plasma concentration within a therapeutic range for a second period, and wherein the dosage form is capable of providing a hyoscyamine plasma concentration within the therapeutic range for a period which is longer than the combined first and second periods.
地址 Fort Worth TX US