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发明名称
細胞結合剤及び細胞毒性剤を含む複合体
摘要
本発明は、CBA−薬物複合体の形成に有用なリンカー化合物及び細胞毒性化合物を提供し、複合体を形成させる。このような複合体及び/または細胞毒性化合物は、比較的低い無毒性投与量で、がん等の疾患領域の治療に比較的高い活性を有して有効であってもよい。【選択図】図1
申请公布号
JP2016510730(A)
申请公布日期
2016.04.11
申请号
JP20150560361
申请日期
2014.02.28
申请人
イミュノジェン・インコーポレーテッド
发明人
ウィジソン,ウェイン・シー
分类号
C07K7/02;A61K39/395;A61K45/00;A61P1/18;A61P13/12;A61P17/02;A61P19/00;A61P19/02;A61P21/00;A61P25/00;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P35/02;A61P37/04;A61P37/06;A61P43/00;C07D498/18;C07K16/30;C12N15/02
主分类号
C07K7/02
代理机构
代理人
主权项
地址
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