发明名称 |
BETA AMINO ACID DERIVATIVES AS INTEGRIN ANTAGONISTS |
摘要 |
Disclosed herein are novel pharmaceutical agents which are useful as integrin receptor antagonists that mediate the pathologic processes of angiogenesis and fibrosis and as such are useful in pharmaceutical compositions and in methods for treating conditions mediated by these integrins by inhibiting or antagonizing these integrins. The novel pharmaceutical agents include those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Methods and intermediates useful for making the pharmaceutical agents and methods of using the pharmaceutical agents are also provided. |
申请公布号 |
HK1209749(A1) |
申请公布日期 |
2016.04.08 |
申请号 |
HK20150110647 |
申请日期 |
2015.10.28 |
申请人 |
SAINT LOUIS UNIVERSITY |
发明人 |
RUMINSKI, PETER P;GRIGGS, DAVID D |
分类号 |
C07D;A61K;A61P;C07C |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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