发明名称 |
PRIMING OF AN IMMUNE RESPONSE |
摘要 |
There is provided inter alia a nucleic acid construct comprising sequences encoding a) at least one invariant chain or variant thereof operatively linked to b) at least one antigenic protein or peptide or an antigenic fragment of said protein or peptide, wherein said nucleic acid construct is used for priming of a cancer vaccine, and/or said invariant chain or variant thereof does not comprise the first 17 amino acids, and/or said invariant chain or variant thereof does not comprise the LRMK amino acid residues of the KEY region, and/or said invariant chain comprises a variant of the CLIP region. |
申请公布号 |
HK1209645(A1) |
申请公布日期 |
2016.04.08 |
申请号 |
HK20150110589 |
申请日期 |
2015.10.28 |
申请人 |
KBENHAVNS UNIVERSITET (UNIVERSITY OF COPENHAGEN) |
发明人 |
HOLST, PETER;THOMSEN, ALLAN;CHRISTENSEN, JAN;GRUJIC, MIRJANA |
分类号 |
A61K;C07K;C12N |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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