发明名称 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE 1-()
摘要 A compound represented by formula (1) (in the formula: ring-D represents a three- to eight-membered hydrocarbon ring; R a represents an optionally substituted amino C 1-6 alkyl group or the like; R b1 and R b2 each independently represent a hydrogen atom, a halogen atom, or the like; R c represents an optionally substituted C 6-10 aryl group or the like; R d represents a hydrogen atom or the like; and ring-Q represents a (hetero)aryl group or the like which may be substituted with a carboxyl group or the like) or a pharmaceutically acceptable salt thereof exhibits an excellent FXIa inhibitory activity, and is useful as a therapeutic agent against thrombosis or the like.
申请公布号 HK1209747(A1) 申请公布日期 2016.04.08
申请号 HK20150110632 申请日期 2015.10.28
申请人 SUMITOMO DAINIPPON PHARMA CO. LTD. 发明人 IKUMA YOHEI;FUKUDA NOBUHISA;IWATA MASATO;KIMURA HIDENORI;SUZUKI KUNIKO
分类号 C07D;A61K;A61P 主分类号 C07D
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