发明名称 |
Vacuna contra el virus de la fiebre del Nilo |
摘要 |
The invention concerns <i>in vivo</i> and <i>in vitro</i> expression vectors comprising a polynucleotide coding for the structural protein E of the Nile fever virus or the WN virus, optionally associated with a polynucleotide coding for the pre-membrane protein prM and/or for the membrane protein M, in particular in the form coding for prM-M-E. Said <i>in vivo</i> expression vectors are incorporated in live vaccines. The <i>in vivo</i> expression vectors are used for producing <i>in vitro</i> proteins which can then be used in subunit vaccines. The invention also concerns multivalent vaccines comprising a vaccine constituent against the WN virus and a vaccine constituent against another pathogen. The invention is particular designed for horses, dogs, cats, cattle, pigs and birds. |
申请公布号 |
ES2566044(T3) |
申请公布日期 |
2016.04.08 |
申请号 |
ES20020759818T |
申请日期 |
2002.04.05 |
申请人 |
MERIAL |
发明人 |
LOOSMORE, Sheena May;AUDONNET, Jean-Christophe Francis;MINKE, Jules Maarten |
分类号 |
C12N1/00;C12N15/09;A61K38/00;A61K39/12;A61K39/275;A61K48/00;A61P31/00;A61P31/12;C07K14/18;C12N15/40;C12N15/863 |
主分类号 |
C12N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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