发明名称 HGH DETERMINATION FOR USE TO GUIDE PREVENTION OF A MAJOR ADVERSE CARDIAC EVENT OR A CARDIOVASCULAR DISEASE IN A SUBJECT
摘要 Subject matter of the present invention is a method of determining whether a subject has a vascular risk that can be reduced by blood pressure lowering therapy with antihypertensive drugs (e.g. Angiotensin converting enzyme inhibitor (ACE inhibitor), Angiotensin Receptor Blocker (ARB), Beta-Adrenoreceptor Blocker (Beta-blocker) and/or statins) comprising the steps: • determining the level of hGH, and/or its isoforms in a blood sample of said subject and • comparing the determined level of hGH, and/or its isoforms in said blood sample with a pre-determined threshold and • wherein in case the determined level of hGH, and/or its isoforms is above said pre-determined threshold then the subject is identified as having a vascular risk that can be reduced by blood pressure lowering therapy with antihypertensive drugs (e.g. Angiotensin converting enzyme inhibitor (ACE inhibitor), Angiotensin Receptor Blocker (ARB), Beta-Adrenoreceptor Blocker (Beta-blocker) and/or statins) and wherein in case the determined level of hGH, and/or its isoforms is below said pre-determined threshold then the subject is identified as not having a vascular risk that can be reduced by blood pressure lowering therapy with antihypertensive drugs (e.g. Angiotensin converting enzyme inhibitor (ACE inhibitor), Angiotensin Receptor Blocker (ARB), Beta- Adrenoreceptor Blocker (Beta-blocker) and/or statins).
申请公布号 WO2016050904(A1) 申请公布日期 2016.04.07
申请号 WO2015EP72675 申请日期 2015.10.01
申请人 SPHINGOTEC GMBH 发明人 BERGMANN, ANDREAS;MELANDER, OLLE;NG, LEONG
分类号 G01N33/68 主分类号 G01N33/68
代理机构 代理人
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