发明名称 |
PSGL-1 MODULATORS AND USES THEREOF |
摘要 |
The present invention relates to the seminal discovery that P-selectin glycoprotein ligand-1 (PSGL-1) modulates the immune system and immune responses. Specifically, the present invention provides PSGL-1 agonists and antagonists which increase the survival of multifunctional T cells and viral clearance. The present invention further provides methods of treating infectious diseases, cancer and immune and inflammatory diseases and disorders using a PSGL-1 modulator. |
申请公布号 |
WO2016007653(A3) |
申请公布日期 |
2016.04.07 |
申请号 |
WO2015US39586 |
申请日期 |
2015.07.08 |
申请人 |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE |
发明人 |
BRADLEY, LINDA, M.;TINOCO, ROBERTO |
分类号 |
A61K39/395;C07K16/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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