COMPOSITIONS AND METHODS FOR SILENCING HEPATITIS B VIRUS GENE EXPRESSION
摘要
The present invention provides compositions comprising therapeutic nucleic acids such as siRNA that target Hepatitis B virus (HBV) gene expression, lipid particles comprising one or more (e.g., a combination) of the therapeutic nucleic acids, and methods of delivering and/or administering the lipid particles (e.g., for treating HBV infection and/or HDV infection in humans).
申请公布号
WO2016054421(A1)
申请公布日期
2016.04.07
申请号
WO2015US53569
申请日期
2015.10.01
申请人
PROTIVA BIOTHERAPEUTICS, INC;CROSS, JENNIFER L.;DHILLON, AMMEN P.;LEE, AMY C.H.;MACLACHLAN, IAN;SNEAD, NICHOLAS M.;THI, EMILY P.
发明人
CROSS, JENNIFER L.;DHILLON, AMMEN P.;LEE, AMY C.H.;MACLACHLAN, IAN;SNEAD, NICHOLAS M.;THI, EMILY P.