发明名称 ARYLALKYLPIPERAZINES FOR USE AS NEUROPROTECTIVE AGENTS
摘要 A compound of the general formula A or a or a pharmaceutically acceptable salt or solvate thereof, wherein: R1 is selected from the group consisting of: C1-C12-alkyl, C3-C12-cycloalkyl, C6- C10-aryl, and C5-C7-heteroaryl; each optionally substituted with halogen, hydroxyl, OCOR3, amino, C1-C6-alkylamino, C1-C6-dialkylamino, C1C6- (halo)alkyl, C1C6-(halo)- alkoxy and/or COOR3; R2 is selected from the group consisting of: C6-C10-aryl and C5-C7-heteroaryl; each optionally substituted with halogen, hydroxyl, OCOR3 amino, C1C6- alkylamino, CrC6-dialkyl- amino, C1-C6-(halo)alkyl, C1C6-(halo)alkoxy and/or COOR3; R3 is independently at each occurrence selected from the group consisting of hydrogen and C1-C2-alkyl; and n is an integer from 1 to 10 inclusive.
申请公布号 WO2016051155(A1) 申请公布日期 2016.04.07
申请号 WO2015GB52822 申请日期 2015.09.29
申请人 UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION 发明人 MAHMOUD, IRAVANI;SOSKIC, VUKIC
分类号 C07D213/71;A61K31/496;A61P25/00 主分类号 C07D213/71
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