发明名称 |
Peptidic chimeric antigen receptor T cell switches and uses thereof |
摘要 |
Disclosed herein are chimeric antigen receptor effector cells (CAR-ECs) and CAR-EC switches. The switchable CAR-ECs are generally T cells. The one or more chimeric antigen receptors may recognize a peptidic antigen on the CAR-EC switch. The CAR-ECs and switches may be used for the treatment of a condition in a subject in need thereof. |
申请公布号 |
AU2014337367(A1) |
申请公布日期 |
2016.04.07 |
申请号 |
AU20140337367 |
申请日期 |
2014.10.15 |
申请人 |
THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
YOUNG, TRAVIS;KIM, CHANHYUK;SCHULTZ, PETER G. |
分类号 |
C07K19/00;A61K38/17;C12N5/07;C12N15/63 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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