| 主权项 |
1. A compound of Formula I or IA: or a pharmaceutically acceptable salt, ester or prodrug thereof; wherein represents a single or double bond; each n, m, p and q is independently selected from 0, 1, 2 and 3; Cy1 is selected from heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic; each R1, R2, R3 and R4 is selected from hydrogen, halogen, alkyl, substituted alkyl, heteroalkyl, substituted heteroalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aliphatic, substituted aliphatic, aryl and substituted aryl, —OR100, —NR100R101, —C(O)R100, —C(O)OR100, —C(O)NR100R101, —N(R100)C(O)R101, —S(O)2R100, —S(O)R100, —SR100, —S(O)2N(R100)R101, —CF3, —CN, —NO2, —N3; alternatively two R1 and R2 groups or two R3 and R4 groups or an R100 and R101 groups together with the atoms to which they are attached and any intervening atoms may form an additional optionally substituted, 3, 4, 5, 6 or 7 membered ring; alternatively, two R3 groups or two R4 groups together may form an oxo, vinyl or substituted vinyl group; and, each R100 and R101 is selected from hydrogen, halogen, alkyl, substituted alkyl, heteroalkyl, substituted heteroalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aliphatic, substituted aliphatic, aryl and substituted aryl. |
