SYNTHESIS OF CELL PENETRATING PEPTIDES FOR DRUG DELIVERY AND STEM CELL APPLICATIONS

摘要

The present invention provides a novel cell penetrating peptide that transports proteins into cells and/or into nuclei and a pharmaceutical containing the peptide. The invention provides a composition comprising a cell penetrating peptide (CPP), wherein the CPP comprises the sequence of AAAAEK (SEQ ID NO: 1) or a variant thereof. In one embodiment, the CPP is linked to a cargo. The invention provides a method of delivering a cargo into a cell. The invention provides a method of treating, preventing or ameliorating a disease in a patient in need thereof.