SYSTEMS AND METHODS FOR IDENTIFYING AND FLAGGING SAMPLES OF CONCERN.

摘要

The present disclosure describes systems and methods for determining and flagging sequences that deviate from one or more reference sequences. Phylogenetic methods are used for determining the evolutionary history and evolutionary distances of sample isolates. The evolutionary distances of sample isolates may be compared to each other and/or reference isolates. Based on a comparison of the evolutionary distances, a determination of deviance is made for a sample sequence. The sample sequence is flagged for further analysis to determine the cause of deviation.