The present invention relates to influenza A virus variants, particularly variants that are resistant to a polymerase inhibitors. Also provided are methods and compositions related to the influenza A virus variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.
申请公布号
WO2016054312(A1)
申请公布日期
2016.04.07
申请号
WO2015US53393
申请日期
2015.10.01
申请人
VERTEX PHARMACEUTICALS INCORPORATED
发明人
LEEMAN, JOSHUA, ROBERT;BYRN, RANDAL;BENNETT, HAMILTON, BARLOW;BARTELS, DOUGLAS, JOHN