发明名称 |
SELECTIVE PACE4 INHIBITORS AND THEIR USE FOR TREATING A CANCER |
摘要 |
Disclosed herein are PACE4 inhibitors, compositions comprising PACE4 inhibitors and their uses thereof for lowering PACE4 activity, reducing cell proliferation, reducing tumor growth, reducing metastasis formation, preventing and/or treating cancer. Also provided are methods for lowering PACE4 activity, reducing the proliferation of a cell, reducing tumor growth and/or treating and preventing cancer. Methods for screening PACE4 inhibitors and cell proliferation inhibitors are further provided. |
申请公布号 |
EP2303910(B1) |
申请公布日期 |
2016.04.06 |
申请号 |
EP20090793747 |
申请日期 |
2009.07.06 |
申请人 |
SOCPRA-SCIENCES SANTÉ ET HUMAINES S.E.C. |
发明人 |
DAY, ROBERT;FUGÈRE, MARTIN;NEUGEBAUER, WITOLD A. |
分类号 |
A61K38/08;A61P35/00;C07K7/06;C07K14/81 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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