发明名称 PROCESS FOR OBTAINING DRONEDARONE
摘要 The present invention provides a process for obtaining dronedarone or salts thereof characterized in that in an organic phase comprising one or more non-polar solvents, 5-amino-3-[4-(3-di-n-butylaminopropoxy)benzoyl]-2-n-butyl-benzofuran is reacted with methane sulfonyl chloride without the addition of a base. The invention also provides a process for obtaining intermediates of dronedarone environmentally friendly and industrially viable..
申请公布号 EP2630131(B1) 申请公布日期 2016.04.06
申请号 EP20110771138 申请日期 2011.10.18
申请人 LABORATORIOS LESVI, S.L. 发明人 VISHNU NEWADKAR, RAVINDRANATH;CHANGDEO GAIKWAD, AVINASH;MADHUKAR HARAD, AJAY
分类号 C07D307/80 主分类号 C07D307/80
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