发明名称 |
PROCESS FOR OBTAINING DRONEDARONE |
摘要 |
The present invention provides a process for obtaining dronedarone or salts thereof characterized in that in an organic phase comprising one or more non-polar solvents, 5-amino-3-[4-(3-di-n-butylaminopropoxy)benzoyl]-2-n-butyl-benzofuran is reacted with methane sulfonyl chloride without the addition of a base. The invention also provides a process for obtaining intermediates of dronedarone environmentally friendly and industrially viable.. |
申请公布号 |
EP2630131(B1) |
申请公布日期 |
2016.04.06 |
申请号 |
EP20110771138 |
申请日期 |
2011.10.18 |
申请人 |
LABORATORIOS LESVI, S.L. |
发明人 |
VISHNU NEWADKAR, RAVINDRANATH;CHANGDEO GAIKWAD, AVINASH;MADHUKAR HARAD, AJAY |
分类号 |
C07D307/80 |
主分类号 |
C07D307/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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